Table_1_Case report: Corticosteroids as an adjunct treatment for the management of liver abscess in Papillon–Lefèvre syndrome: A report on two cases.DOCX

Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder characterized clinically by palmoplantar keratoderma, periodontitis, and recurrent pyogenic infections. Liver abscess is rarely reported in patients. The use of corticosteroids for the treatment of liver abscess akin to chronic granulomatous disease (CGD) has not been reported previously. Here, we report 2 cases of liver abscess in PLS that responded to corticosteroids.

蝴蝶-莱弗弗尔综合征（Papillon–Lefèvre 综合征，PLS）是一种罕见的常染色体隐性遗传疾病，其临床特征表现为掌跖角化过度、牙周炎以及复发性化脓性感染。肝脏脓肿在患者中的报道极为罕见。类似于慢性肉芽肿性疾病的（CGD）使用皮质类固醇治疗肝脏脓肿的方法此前未曾有报道。在本研究中，我们报告了两例PLS患者发生肝脏脓肿的病例，且这些病例对皮质类固醇治疗产生了反应。