Additional file 8 of Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer

Additional file 8: Table S8. Cox regression between our event signature and traditional clinicopathological parameters. (a) Univariate and multivariate Cox regression of the alternative splicing event signature and clinicopathological factors with respect to the biochemical recurrence-free survival of prostate cancer patients in the TCGA-PRAD training set. TCGA: The Cancer Genome Atlas; PRAD: prostate adenocarcinoma; Age: age at diagnosis; T stage: tumour stage; N stage: lymph node status (N0 = without lymph node metastasis; N1 = with lymph node metastasis). HR: hazard ratio of the parameter; HR.95L: the lower limit of 95% confidence interval; HR.95H: the upper limit of the 95% confidence interval; p: p-values obtained from the likelihood ratio test. (b) Univariate and multivariate Cox regression of the alternative splicing event signature and clinicopathological factors with respect to the biochemical recurrence-free survival of prostate cancer patients in the TCGA-PRAD testing set. TCGA: The Cancer Genome Atlas; PRAD: prostate adenocarcinoma; Age: age at diagnosis; T stage: tumour stage; N stage: lymph node status (N0 = without lymph node metastasis; N1 = with lymph node metastasis). HR: hazard ratio of the parameter; HR.95L: the lower limit of 95% confidence interval; HR.95H: the upper limit of the 95% confidence interval; p: p-values obtained from the likelihood ratio test. (c) Univariate and multivariate Cox regression of the alternative splicing event signature and clinicopathological factors with respect to the biochemical recurrence-free survival of prostate cancer patients in the TCGA-PRAD complete set. TCGA: The Cancer Genome Atlas; PRAD: prostate adenocarcinoma; Age: age at diagnosis; T stage: tumour stage; N stage: lymph node status (N0 = without lymph node metastasis; N1 = with lymph node metastasis). HR: hazard ratio of the parameter; HR.95L: the lower limit of 95% confidence interval; HR.95H: the upper limit of the 95% confidence interval; p: p-values obtained from the likelihood ratio test..