Electrochemical Trifluoromethylthiolation/Cyclization of <i>N</i>‑Arylacrylamides with AgSCF<sub>3</sub>: Access to SCF<sub>3</sub>‑Containing Oxindoles
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An environmentally friendly electrochemical strategy for the synthesis of SCF3-containing oxindoles was developed. This electrochemical transformation was accomplished through a cascade trifluoromethylthiolation/cyclization of N-acrylamides with AgSCF3, obviating the requirement for external oxidants. A variety of functional groups were well tolerated in this transformation.
创建时间：
2024-08-19
