Suppression of Notch during efferocytosis prevents macrophages inflammatory polarization [RNA-seq.HumanMouse]
收藏NIAID Data Ecosystem2026-05-10 收录
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资源简介：
We investigated the mechanism of suppression of Notch during efferocytosis. Genetically activation of Notch or ablation of Rubicon in marophages induced pro-inflammatory polarization and enhance anti-tumor effect. Overall design: We performed RNA seq and slam-seq in the presence or abscence of apoptotic Jurkat cells to study how genes expression is regulated during efferocytosis in different genotypes.
创建时间：
2026-01-09
