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Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976 Descriptor: 1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 Authors: Lountos, G.T, Jobson, A.G, Tropea, J.E, Self, C.R, Pommier, Y, Shoemaker, R.H, Zhang, G, Waugh, D.S. Deposit date: 2011-03-16 Release date: 2011-11-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy. J.Struct.Biol., 176, 2011

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2011-03-16
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