Transcriptomic study of NR8383 rat macrophages cells following exposure to zinc iron oxide (ZnFe2O4, NRCWE021)

To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 17 µg/mL of zinc iron oxide (ZnFe2O4, NRCWE021). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098为鉴定纳米材料暴露后引发毒性的差异表达基因与关键生物通路，我们对暴露于17 µg/mL锌铁氧体（zinc iron oxide, ZnFe₂O₄，编号NRCWE021）的NR8383巨噬细胞开展了4小时的微阵列分析（microarray）。本项目获得欧盟地平线2020研究与创新计划（Horizon 2020）资助，资助协议编号为686098。