EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7jxk
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EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02 Descriptor: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... Authors: Beyett, T.S, Eck, M.J. Deposit date: 2020-08-27 Release date: 2021-09-08 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors Nat Commun, 13, 2022
创建时间：
2020-08-27
