CBFb Stabilizes HIV Vif to Counteract APOBEC3 at the Expense of RUNX1 Target Gene Expression

ChEBI2013-01-17 更新2026-07-21 收录

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病毒-宿主蛋白相互作用

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42576 数据链接链接失效反馈

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CBFb Stabilizes HIV Vif to Counteract APOBEC3 at the Expense of RUNX1 Target Gene Expression

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2013-01-17

Natural Selection Promotes Antigenic Evolvability

病毒抗原进化

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The hypothesis that evolvability - the capacity to evolve by natural selection - is itself the object of natural selection is highly intriguing but remains controversial due in large part to a paucity

NIAID Data Ecosystem100

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

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细胞功能调控

Immune evasion is now recognized as a key feature of cancer progression. In animal models, the activity of cytotoxic lymphocytes is suppressed in the tumour microenvironment by the immunosuppressive c

Figshare2016-01-18 更新40

SARS-CoV-2 Nsp1 N-terminal and linker regions as a platform for host translational shutoff_CLMS_DSSO_dataset

病毒-宿主蛋白相互作用

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In the early stages of SARS-CoV-2 infection, non-structural protein 1 (Nsp1) inhibits the innate immune response by inserting its C-terminal helices into the mRNA entry channel of the ribosome and pro

NIAID Data Ecosystem30

Gli2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating Wnt Ligand and Prostaglandin Synthesis [scRNAseq]

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Therapeutic resistance to immune checkpoint blockade remains a prevalent obstacle across many cancer types, and an improved mechanistic understanding of this process could lead to effective combinatio

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DataSheet_1_PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.docx

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胶质母细胞瘤免疫治疗靶点

BackgroundImmunotherapy, especially checkpoint inhibitors targeting PD-1 or PD-L1, has revolutionized cancer therapy. However, PD-1/PD-L1 inhibitors have not been investigated thoroughly in glioblasto

NIAID Data Ecosystem30

CBFb Stabilizes HIV Vif to Counteract APOBEC3 at the Expense of RUNX1 Target Gene Expression

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