How does amyloid-beta protein interact with raft-model membrane and affect it...
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Alzheimer's disease. Alzheimer's disease
ES-derived neural cells Overall design: Alzheimer's disease vs. healthy controls
NIAID Data Ecosystem60
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Last modified: 2025
Protein Data Bank Japan2025-07-02 更新20
Exercise alleviates cognitive dysfunction in Alzheimer's disease mice via skeletal muscle-derived extracellular vesicles which enhance plaque clearance by microglia [RNA-Seq]
Exercise confers cognitive benefits in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. The skeletal muscle functions as an endocrine organ that secretes myokine
NIAID Data Ecosystem00
source data for fig5bcd
RyanR2-E4872Q (EQ) mutation promotes APP degradation through autophagic pathway
NIAID Data Ecosystem30
Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides
Alzheimer's disease (AD) is characterized by the age-related deposition of β-amyloid (Aβ) 40/42 peptide aggregates in vulnerable brain regions. Multiple levels of evidence implicate a central role for
PubMed Central2000-02-01 更新10
