Cyp21a1
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ENCODES a protein that exhibits steroid 21-monooxygenase activity; 17-hydroxyprogesterone 21-hydroxylase activity (ortholog); heme binding (ortholog); INVOLVED IN C21-steroid hormone biosynthetic process; cellular response to peptide hormone stimulus; mineralocorticoid biosynthetic process; PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH congenital adrenal hyperplasia (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH atorvastatin calcium; bisphenol A; caffeine
编码一种表现出类固醇21-单加氧酶活性(同源)的蛋白质;17-羟基孕酮21-羟化酶活性(同源);血红素结合(同源);参与C21-类固醇激素生物合成过程;细胞对肽类激素刺激的响应;盐皮质激素生物合成过程;参与醛固酮生物合成途径;皮质醇生物合成途径;类固醇激素生物合成途径;与先天性肾上腺增生(同源)相关;存在于内质网膜中(推断);与阿托伐他汀钙、双酚A、咖啡因相互作用。
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