Transcriptional profiling of macrophages in Blau syndrome
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA673083
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资源简介:
We aimed to characterize the transcriptional profiles of macrophages generated from peripheral blood monocytes of Blau syndrome patients, untreated or treated with anti-TNF antibodies. Given our previous finding that IFNg stimulation is a key priming signal for Blau syndrome-associated inflammatory responses, we conducted RNA-seq with or without IFNg stimulation. Moreover, we generated patients' iPSC-derived macrophages and compared the transcriptional profiles with WT counterparts.
创建时间:
2020-10-29



