IRF4/BATF and interleukin-33 orchestrate development and maintenance of adipose tissue resident regulatory T cells

ChEBI2014-12-11 更新2026-07-21 收录

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调节性T细胞功能

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IRF4/BATF and interleukin-33 orchestrate development and maintenance of adipose tissue resident regulatory T cells

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2014-12-11

Microbial Energy Metabolism Fuels a CSF2-dependent Intestinal Macrophage Niche within Solitary Isolated Lymphoid Tissues via purinergic signaling.. Microbial Energy Metabolism Fuels a CSF2-dependent Intestinal Macrophage Niche within Solitary Isolated Lymphoid Tissues via purinergic signaling.

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巨噬细胞生态位

Gene expression comparison across CD11b+ cells from Csf2-sufficient and deficient mice. Overall design: Steady state isolated CD11b+ cells from colon lamina propria or solitary isolated lymphoid tissu

NIAID Data Ecosystem70

Expression of HPGD in regulatory T cells prevents adipose tissue inflammation and metabolic dysfunction (data set 2)

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脂肪组织稳态与代谢疾病

Regulatory T cells (Treg cells) are important for the prevention of autoimmunity and lately, their role in maintaining tissue homeostasis has been demonstrated. They exert their function via different

NIAID Data Ecosystem30

Additional file 2 of DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections

病毒感染表观遗传学

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Additional file 2. Supplementary Table 1. Description of animals used for characterization of DNA methylation during SIV infection.

NIAID Data Ecosystem30

D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses

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巨噬细胞炎症抑制

Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up

NIAID Data Ecosystem30

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

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PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

NIAID Data Ecosystem30

IRF4/BATF and interleukin-33 orchestrate development and maintenance of adipose tissue resident regulatory T cells

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