Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells
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https://www.ncbi.nlm.nih.gov/sra/SRP149631
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资源简介:
The human pluripotent stem cells cultured on Low-adhesion substrates formed two morphologically different subtypes (Monolayer and Domed). The dome-like cells showed higher proliferation capacity and KLF4/5 expression than the monolayer cells. A serum response factor based regulatory double loop was proposed to explain how cell-matrix adhesion mediates the interaction between cell morphology and pluripotency genes Overall design: Compare the two type cells with RNA-seq to investigate the different expression
创建时间:
2019-09-23



