Highly efficient CRISPR-mediated base editing for the gut Bacteroides spp. with pnCasBS-CBE
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
We constructed a pnCasBS-CBE system for base editing in the Bacteroides thetaiotaomicron to expand their genetic toolkit, which can efficiently convert a C:G to a T:A in the genome. As a functional proof-of-concept, we used the pnCasBS-CBE system to successfully introduce nonsynonymous mutation and stop codons to the genes involved in carbohydrate metabolism
创建时间：
2023-01-04
