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Transcriptomic analysis of Caenorhabditis elegans treated with mitochondrial Na+/Ca2+ exchanger inhibitor CGP37157 vs untreated control.

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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We report that CGP37157 improved the evolution with age of the sarcomeric regular structure, delaying development of sarcopenia in C. elegans body wall muscle. Similarly, CGP37157 favoured the maintenance of a regular mitochondrial structure during aging. CGP37157 induced a four-fold increase in the expression of ncx-6, one of the C. elegans mitochondrial Na+/Ca2+ exchangers.

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2022-02-20
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