List of the most conserved DENV3 peptides for which immunogenicity in HLA-DR02, -DR03 and -DR04 transgenic mice was supported by binding affinity analysis to the respective HLA.
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A representative ELISPOT data is shown along with the minimum peptide concentration that activated memory T-cells (functional avidity) is included. In addition, IC50 (nM) for HLA-DR02, -DR03 and -DR04 as well as the number of additional potential HLA binders (as many as 11) are also shown. Binding affinity is characterized by IC50 below 1000 nM (in bold). Pan-dengue conserved sequences are shown underlined.
创建时间:
2013-10-10



