Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium

Mutations that attenuate Salmonella Typhimurium can emerge and destabilize cooperative virulence during infection. We asked if horizontal gene transfer of alleles encoding virulence could restore and maintain virulence. This sequencing bioproject investigates the genetic basis for loss of virulence in isolates in which virulence has been restored, but then subsequently lost once again.