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Dynamics of epigenetic regulation of gene expression during Plasmodium falciparum life cycle

ChEBI2013-03-02 更新2026-07-21 收录

疟原虫表观遗传学

基因表达调控动态

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39238 数据链接链接失效反馈

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Dynamics of epigenetic regulation of gene expression during Plasmodium falciparum life cycle

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2013-03-02

疟原虫表观遗传学

基因表达调控

Variation of surface adhesins is a critical mediator of virulence and immune evasion in many medically important microbes. Phenotypic switching has been linked to transcriptional changes and the funct

NIAID Data Ecosystem30

Auxotrophs of Plasmodium falciparum dependent on p-aminobenzoic acid for growth.

疟原虫表观遗传学

抗疟药物靶点

The isolation of auxotrophic strains of a parasite offers new opportunities for studying parasitology. We have isolated cloned lines of Plasmodium falciparum that, unlike the parent line from which th

PubMed Central1994-05-10 更新20

疟原虫表观遗传学

寄生虫转录组

Chromatin structure is a basal epigenetic mechanism that determines cellular fate by organizing the dynamic gene expression during the cell development and proliferation. The nuclear members of the ev

NIAID Data Ecosystem20

An exon DNA element modulates heterochromatin spreading in the master regulator for sexual commitment in malaria parasites

疟原虫表观遗传学

染色质调控

Heterochromatin is essential in all eukaryotic systems to maintain genome integrity, long-term gene repression and to help chromosome segregation during mitosis. However, heterochromatin regions must

NIAID Data Ecosystem30

The chromatin-bound proteome of the human malaria parasite, Plasmodium falciparum

疟原虫表观遗传学

染色质相关蛋白组学

P. falciparum chromatin is highly structured at the three-dimensional (3D) level, and this structure provides an epigenetic mechanism for gene expression regulation. To investigate how parasite nuclea

NIAID Data Ecosystem20

Dynamics of epigenetic regulation of gene expression during Plasmodium falciparum life cycle

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