Spectral library search can enable more sensitive peptide identification in tandem mass spectrometry experiments. However, its drawbacks are the limited availability of high-quality libraries and the
The automated processing of data generated by top down proteomics would benefit from improved scoring for protein identification and characterization of highly related protein forms (proteoforms). Her
native top-down MS data of human protamines collected on orbitrap fusion lumos. Samples were collected from different patient populations, namely normal, asthenozoospermia, and oliogoasthenozoospermia