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pathogenesis and target therapy of leukemia
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2024-07-29
相关数据集
Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
NIAID Data Ecosystem50
Genome wide mapping of IKAROS binding (ChIP-Seq) in human patient-derived BCR-ABL1+ (Ph+) pre-B ALL xenograft cells
IKAROS is an important tumor suppressor in human pre-B ALL and is mutated or deleted in a high percentage of human BCR-ABL1+ (Ph+) pre-B ALL. We here report the genome-wide binding of IKAROS in two in
NIAID Data Ecosystem30
Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer (RNA-Seq)
Activating estrogen receptor alpha (ER) mutations are present in primary endometrial and metastatic breast cancers, promoting estrogen-independent activation of the receptor. Functional characterizati
NIAID Data Ecosystem20
Primers and probes for 3-plex RT-qPCR of PML-RARa and ABL.
aProbe (r) = Reverse TaqMan MGB probe; PML primer 1 for bcr1, bcr2 and bcr3; PML primer 5 for bcr1 and bcr2; PML primer 6 for bcr3Primers and probes for 3-plex RT-qPCR of PML-RARa and ABL.
Figshare2015-12-03 更新30
Supplementary Table S13 from Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk
Up-regulated pathways in STAG2/LMO2 subtype compared to other T-ALL cases analyzed by gene-set enrichment analysis (GSEA).
NIAID Data Ecosystem20
