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Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program

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NIAID Data Ecosystem2026-04-25 收录
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We report scRNA-seq of in vitro morphine treated PBMCs reveals suppression of anti-viral genes in various immune cell types. Overall design: PBMCs were treated in vitro with morphine for 24 hours, followed by LPS stimulation for 3 hours in vitro. We have used an antibody-based cell hashing technique to multiplex samples in droplet based scRNA-seq.

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2020-06-09
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