Cediranib/SC68896 treatment slows tumor growth and increases mouse survival.

A) Representative T2 weighted coronal mouse brain MR images obtained at 7 days after tumor growth initiation for the four treatment groups. B) Tumor growth curves are shown for the four treatment groups, in tumor volume versus time after tumor growth initiation. Curves are indicated for time points corresponding to ≥3 surviving mice, *: pC) Mean exponential growth rate constants are shown for the four treatment groups, *: pD) Kaplan-Meier survival curves for the four treatment groups (in days from tumor growth initiation), *: p