The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,
To elucidate the mechanism of ALDH18A1-driven gastric carcinogenesis and identify its downstream transcriptional targets, we conducted genome-wide RNA sequencing in HGC-27 cells knockdowning ALDH18A1,
Constitutively active MYC and reactivated telomerase often co-exist in cancers. While the reactivation of telomerase is thought to be essential for replicative immortality, MYC, in conjunction with co
Junctional adhesion molecule-like protein (JAML), a newly discovered junctional adhesion molecule (JAM), mediates the adhesion and migration processes of various immune cells and endothelial/epithelia