A summary of prionogenic (Amyloid Prion Type Am) and candidate-prionogenic sequences in the PrionHome database from Saccharomyces cerevisiae, that have N/Q and F/Y compositional biases.
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*F/Y compositional biases with binomial P-values−6 are considered (see Database Construction & Content for details).**This data includes the Alberti, et al. (2009) data from screens for candidate prionogenic sequences.***As an example, the SQL query to obtain this data is: SELECT prion_id , name FROM main WHERE prion_type LIKE’%prionogenic%’ AND bias REGEXP ‘Y|F’ AND bias REGEXP ‘N|Q’ AND organism LIKE ‘%cerevisiae%’.****Polymorphic sequences have been removed from these totals. This is the total list of Prion-Like sequences from Harrison, et al. (2006) and Alberti, et al. (2009).*****Prion-like sequences that failed to form amyloid by any tests in Alberti, et al. (2009).
创建时间:
2015-12-02




