Sequence-selective polyamide design against HSV origin OBP boxes: human co-occurrence analysis of half-site and dual-register architectures (computational package v1.1)

Computational genome co-occurrence scans and paper designs for programmable polyamide architectures targeting an HSV-1/2 origin OBP-box 19-mer. Includes human (hg38) exact and Hamming-bounded counts, dual-register co-occurrence results, coordinates for 13 Hamming<=1 abutting human loci, the single human Hamming<=2 residual (chr2:239,811,937-239,811,955), frozen viral RefSeq panel (NC_001806.2, NC_001798.2), and scanner scripts. Not a drug. No efficacy claims. Research-use / paper design only. Correspondence: [e-mail].