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Crystal structure of the KRAS-p110alpha complex in the presence of molecular glue D223

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Protein Data Bank Japan2025-08-06 更新2026-04-19 收录
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https://pdbj.org/mine/summary/9cmv
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Crystal structure of the KRAS-p110alpha complex in the presence of molecular glue D223 Descriptor: GLYCEROL, GTPase KRas, MAGNESIUM ION, ... Authors: Czyzyk, D.J, Yan, W, Simanshu, D.K. Deposit date: 2024-07-15 Release date: 2025-07-23 Last modified: 2025-08-06 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Molecular glues that facilitate RAS binding to PI3K alpha promote glucose uptake without insulin. Science, 389, 2025
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2024-07-15
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