RNAseq of 6 genome edited human RPE1 cell lines (compared to the parental control) disrupting the MIA3 gene.. RNAseq of 6 genome edited human RPE1 cell lines (compared to the parental control) disrupting the MIA3 gene.

We generated 6 cell lines disrupting the MIA3 gene using CRISPR/Cas9. We have then run RNAseq to compare these 6 lines to the control (Wild-type (WT) parental cell line). The aim of the study was to define changes in the transcriptome following loss of different isoforms of the TANGO1 protein encoded by the Mia3 gene. These data are linked to proteomic data submitted to PRIDE with accession numbers PXD024214 and PXD024221.