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RUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis

ChEBI2016-01-04 更新2026-07-12 收录

造血干细胞

基因表达谱系定向

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68958 数据链接链接失效反馈

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资源简介：

RUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis

应用场景：

创建时间：

2016-01-04

造血干细胞

表观遗传学

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Hematopoietic stem cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia [RNASeq_Cdx2_secondaryAML]

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The caudal-related homeobox transcription factor CDX2 is ectopically expressed in the majority of patients with acute myeloid leukemia (AML). We generated an inducible transgenic mouse model whereby C

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Genome-wide definition of regulatory elements in hematopoietic stem cell differentiation

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启动子使用分析

Cap Analysis of Gene Expression (CAGE) was used to define the promoter usage in HSPC and their committed progeny.

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Prospective identification and lineage tracing of top-level hematopoietic stem cells that sustain adult hematopoiesis

造血干细胞鉴定

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Hematopoietic stem cells (HSC) sustain long-term reconstitution of hematopoiesis in primary transplantation recipients. Few HSC can serially reconstitute secondary recipients, and their identity and c

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Additional file 3 of Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

DNA甲基化

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Additional file 3. Table S5. Table with calculation of mean beta-values and variances for selection of candidate CpGs.

DataCite Commons2025-10-29 更新70