The role of RPA1 in T cells [thymus]
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
As a single strand DNA binding protein, RPA1 participates in various cellular processes including DNA replication and DNA repair. However, the role of RPA1 in T cells is largely unknown. We generated a mouse model in which RPA1 was specifically deleted in T cells. Through single cell RNA sequencing, we reveal the immune landscape in RPA1 conditional knockout mice. Overall design: Study of immune cells in thymus from WT or RPA1 conditional knockout mice using 10x scRNA-seq technologies.
创建时间：
2024-06-16
