Comparison of cortical grey matter from Rasmussen Encephalitis patients and age-matched epileptic controls

We performed whole-genome transcriptome analysis of Rasmussen Encephalitis of the early disease stages for an overview of differentially expressed pathways leading to widespread neuroinflammation and degeneration. This study was done on FFPE surgical resection material from patients suffering from Rasmussen Encephalitis and epileptic controls (age matched tumour patients). We included patients from Rasmussen Encephalitis stage 0 - 2 (no inflammation - acute inflammation). Controls (n=7), RE stage 0 (n= 5), RE stage 1 (n= 6), RE stage 2 (n=6)