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Crystal structure of human cathepsin L in complex with covalently bound CLIK148

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Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Crystal structure of human cathepsin L in complex with covalently bound CLIK148 Descriptor: (2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N'-(2-pyridin-2-ylethyl)butanediamide, 1,2-ETHANEDIOL, Cathepsin L, ... Authors: Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Tsuge, H, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. Deposit date: 2022-05-15 Release date: 2023-11-29 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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2022-05-15
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