Single-Cell Transcriptomic and Chromatin Accessibility Atlas of Peripheral Blood Mononuclear Cells Reveal the Immune Cell Heterogeneity of Pigs

<strong>The study represents the most comprehensive single-cell transcriptomic and regulatory profiling of porcine PBMCs from two distinct breeds at unprecedented resolution. This study improves our understanding about the immune heterogeneity and inter-breed immune trait variations in pigs. We also expect the cell sub-populations, immune markers and core regulators identified in this study would be valuable in facilitating future biomedical studies about human immunology and organ xenotransplantation</strong>.