Structure of liver pyruvate kinase in complex with allosteric modulator 20

Structure of liver pyruvate kinase in complex with allosteric modulator 20 Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, N-{[4-(3,4-dihydroxybenzene-1-sulfonyl)phenyl]methyl}-N-(3,4-dihydroxyphenyl)-3,4-dihydroxybenzene-1-sulfonamide, ... Authors: Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. Deposit date: 2022-12-18 Release date: 2023-04-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.774 Å) Cite: Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023