Association P-values and effect-size estimates for rs656843 in the discovery and replication samples.

a,b Case-control sample
c Discovery and replication sample I combined using meta-analysis
d Prospective sample
e Hazard ratio
MAF, minor allele frequency;
OR, odds ratio;
MI, myocardial infarction;
STEMI, ST elevation myocardial infarction;
NSTEMI, non-ST elevation myocardial infarction;
na., not applicable
Case-control samples analyzed using logistic regression including age, sex, and the first ten genomic principal components (the discovery sample) or no covariates (Replication sample I) in the model. Replication sample II analyzed using the Cox proportional hazards model stratified by study year, geographical region, and genotyping batch with gender, systolic blood pressure, blood pressure medication, total cholesterol, HDL-cholesterol, smoking and diabetes used as covariates. Sample sizes (for the MAFs) and 95% confidence intervals (for the OR/hazard ratio estimates) are reported in parentheses.
Association P-values and effect-size estimates for rs656843 in the discovery and replication samples.