Tossing monkey wrenches into the clock: New ways of treating cancer

Name: Tossing monkey wrenches into the clock: New ways of treating cancer
Creator: National Academy of Sciences
Published: 1999-04-13T00:00:00+08:00

PubMed Central1999-04-13 更新2026-05-02 收录

时间治疗学

肿瘤靶向治疗创新

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https://pmc.ncbi.nlm.nih.gov/articles/PMC33556/数据链接链接失效反馈

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Tossing monkey wrenches into the clock: New ways of treating cancer

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National Academy of Sciences

创建时间：

1999-04-13

Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding.

转录因子相互作用

TATA盒结合蛋白

Transcription initiation factor TFIID plays a central role in transcriptional regulation. Drosophila TFIID is a multimeric protein consisting of the TATA box-binding polypeptide (TBP) and a number of

PubMed Central1994-04-26 更新10

Comparison of directional selectivity in identified spiking and nonspiking mechanosensory neurons in the crayfish Orconectes limosus.

神经生理学

神经元方向选择性

We have recorded electrical activity from two identified synaptically coupled mechanosensory interneurons in the abdominal nervous system of the crayfish Orconectes limosus and have studied their resp

PubMed Central1994-06-21 更新00

Adenovirus early region 4 stimulates mRNA accumulation via 5' introns.

病毒基因表达调控

mRNA剪接与稳定性

The adenovirus major late transcription unit accounts for most virus-specific transcription late after infection. All mRNAs expressed from this unit carry a short spliced leader, the so-called tripart

PubMed Central00

Selenium redox biochemistry of zinc–sulfur coordination sites in proteins and enzymes

锌-硫配位氧化还原

硒生物地球化学

Selenium has been increasingly recognized as an essential element in biology and medicine. Its biochemistry resembles that of sulfur, yet differs from it by virtue of both redox potentials and stabili

PubMed Central1999-03-02 更新00

Transgenic mouse model of malignant skin melanoma.

黑色素瘤模型

皮肤癌机制

Tyr-SV40E transgenic mice are specifically susceptible to melanoma due to expression of the oncogene in pigment cells. Mice of the more susceptible lines die young of early-onset eye melanomas, when s

PubMed Central1993-10-01 更新00

Tossing monkey wrenches into the clock: New ways of treating cancer

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