We used a combination of genetic and proteomic approaches to characterize tmRNA (ssrA) activity in the genome-reduced bacterium Mycoplasma pneumoniae. For this, we generated tmRNA mutants encoding a t

NIAID Data Ecosystem00

Epitranscriptomics m6A analyses reveal distinct m6A marks in tumor necrosis a (TNF-a)-treated HeLa cells. Epitranscriptomics m6A analyses reveal distinct m6A marks in tumor necrosis a (TNF-a)-treated HeLa cells

RNAm6A甲基化

细胞信号通路

We have performed a epitranscriptomics study in which we first tretaed TNF-alpha in HeLa cells and DMSO was used as a negative control. Total RNA was isolated from TNF-alpha treated cells as well as c

NIAID Data Ecosystem20

Adaptive evolution of Geobacter sulfurreducens and Pseudomonas aeruginosa cocultures

细菌共培养进化

蛋白质组学分析

This study further investigates the previously observed syntrophic interaction between Geobacter sulfurreducens and Pseudomonas aeruginosa. In early coculture establishment, two genetic variants of G.

NIAID Data Ecosystem00

Reverse Phase Protein Array (RPPA) targets, values, signaling pathways.

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