Crystal structure of KPC-2 with hydrolyzed faropenem (ring-open form)
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Crystal structure of KPC-2 with hydrolyzed faropenem (ring-open form) Descriptor: (2~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-butyl-2,3-dihydro-1,3-thiazole-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, ... Authors: Tooke, C.L, Hinchliffe, P, Spencer, J. Deposit date: 2020-08-24 Release date: 2021-02-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Faropenem reacts with serine and metallo-beta-lactamases to give multiple products. Eur.J.Med.Chem., 215, 2021
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2020-08-24
