Characterization of intestine specific TRPM6 knockout C57BL/6J mice: effects of short-term omeprazole treatment
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243832
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The transient receptor potential melastatin type 6 (TRPM6) is a divalent cation channel pivotal for gatekeeping Mg2+ balance. To study the role of TRPM6 in the intestine, we generated mice lacking intestinal TRPM6 (Vill1-TRPM6-/-). In this study, the distal colon of Vill1-TRPM6-/- mice and of the control mice (TRPM6fl/fl) was subjected to RNA sequencing. Total RNA from the distal colon of Vill1-TRPM6-/- and TRPM6fl/fl control mice following 1 day of low Mg2+ diet (0.02% w/w) was extracted. Furthermore, these RNA samples were subjected to RNA-sequencing.
创建时间：
2025-02-12
