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Role of Cebpd on transcriptional output in 4T1 mouse triple negative breast cancer cells

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NIAID Data Ecosystem2026-03-12 收录
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Cebpd is a transcription factor regulating cytokines. We determined the role of Cebpd in the regulation of transciptional output. We generated 4T1 breast cancer cells with CRISPR/Cas9 mediated Cebpd knockout. We treated control sgRosa26 and sgCebpd cells with vehicle or IFNgamma (20ng/ml) for 24 hours and isolated RNA for sequencing. Overall design: Examination of transcriptome in Cebpd intact and Cebpd loss 4T1 breast cancer cells in response to IFNgamma.

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2021-04-29
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