Estimated burden of chronic pulmonary aspergillosis (CPA) complicating pulmonary tuberculosis (TB) in adult Indian population for different rates of annual attrition (death and/or surgical resection) and CPA frequency estimates.

The annual incident cases of CPA were derived in pulmonary TB survivors at 1 year assuming a 22% prevalence of cavitation following pulmonary TB (sensitivity analysis at 10% and 30%). The rate of occurrence of CPA following cavitary pulmonary TB and non-cavitary pulmonary TB was assumed to be 22% (sensitivity analysis at 10% and 30%) and 2% (sensitivity analysis at 1% and 4%), respectively; which provided the annual incident CPA cases. The five year prevalence of CPA was estimated assuming an annual death rate in CPA of 15% (sensitivity analysis at 10% and 25%). Estimated burden of chronic pulmonary aspergillosis (CPA) complicating pulmonary tuberculosis (TB) in adult Indian population for different rates of annual attrition (death and/or surgical resection) and CPA frequency estimates.