* these p-values were calculated with both gender and time in the model, but with no interaction termBaseline and 12-month follow-up serum E2, T and LH.
Variables are expressed as medians (range) or n (%). NS, not significant (P > 0.05); NYHA, New York Heart Association; AST, aspartate aminotransferase; POD, postoperative day; ALT, alanine aminotransf