co-crystal structure of compound 1 bound to human Mcl-1
收藏Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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co-crystal structure of compound 1 bound to human Mcl-1 Descriptor: (4S,7aR,9aR,10S,11E,18R)-6'-chloro-10-[2-(3,3-difluoroazetidin-1-yl)ethoxy]-N-(dimethylsulfamoyl)-18-hydroxy-15-methyl-16-oxo-3',4',7,7a,8,9,9a,10,13,14,15,16,17,18-tetradecahydro-2'H,3H,5H-spiro[1,19-(ethanediylidene)cyclobuta[n][1,4]oxazepino[4,3-a][1,8]diazacyclohexadecine-4,1'-naphthalene]-18-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1 Authors: Huang, X, Whittington, D. Deposit date: 2019-09-18 Release date: 2019-12-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an alpha-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. J.Med.Chem., 62, 2019
创建时间：
2019-09-18
