We found that CTCF sites was acetylated at H3K27 and this modification was decreased by histone acetyltransferases and depletion of GATA-1. Overall design: CTCF and H3K27ac ChIP-seq was performed in c

NIAID Data Ecosystem70

Elucidating the landscape of genome-wide chromatin interaction sites of the lncRNA TUG1 in bovine cell lines and liver tissue

非编码RNA基因组学

染色质互作

Long-noncoding RNA (lncRNA) interact with DNA, RNA and proteins to regulate the epigenome and fundamental biological processes. In the bovine genome, the nature and mechanisms of lncRNA interactions w

NIAID Data Ecosystem20

MS Analysis Reveals the Potential Signaling Pathway for RFWD2 Function in multiple myeloma

骨髓瘤研究

蛋白质信号通路

MS Analysis Reveals the Potential Signaling Pathway for RFWD2 Function in multiple myeloma

integrated proteome resources80

The nuclear matrix associating protein HNRNPU functions as a key regulator of 3D genome architecture [Hi-C]

三维基因组结构

染色质互作

Higher-order chromatin conformation plays critical role in regulating gene expression and biological development, here we show that HNRNPU, a nuclear matrix attachment factor, is a regulator of 3D gen

NIAID Data Ecosystem30

ena-DATASET-ICR-PTGT-30-08-2017-16:23:21:137-250 - samples

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