QPCTL deletion results in a rewiring of the tumor microenvironment [scRNA-seq]

single cell RNA sequencing performed on the FACS sorted tumor microenvironment of (QPCTL-proficient and -deficient) B16F10 tumors C57/Bl6JR mice that were QPCTL-WT or QPCTL-KO were innoculated with either QPCTL-proficient or deficient B16F10 tumor cells, respectively (n=3 each). After 14 days tumors were harvested, single cell suspensions were made and live cells were isolated by FACS, after which cells were processed for scRNA-seq (10X Chromium 3' kit), and sequenced on Illumina NextSeq