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Genome wide map of Runx3 bound regions in murine splenic CD8 T cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP301210
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资源简介:
Runx3 is an important transcription factor for the proper development of CD8+T cells. The number and functionality of CD8+T cells is severely affected in the absence of Runx3. To gain insight into the transcriptional program managed by Runx3 in CD8+T cells we conducted ChIP-seq on 50 million cells and CUT&RUN on 150,000 cells, using anti Runx3 antibodies. Both assays revealed similar results. Overall design: we isolated adult murine CD8 T cells from spleen and analyzed the genomic occupancy of Runx3 either by ChIP or CUT&RUN
创建时间:
2021-01-12
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