Genome-wide effect of ZBP1-mediated inflammatory response to LPS

NIAID Data Ecosystem2026-03-13 收录

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巨噬细胞炎症

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE195687 数据链接链接失效反馈

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资源简介：

We report the role of ZBP1 in mediating responses to LPS in the mouse macrophages. Primary macrophages from wild type and ZBP1-deficient mice were activated for 4 hours with TNF.

创建时间：

2022-01-31

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

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炎症与表观遗传调控

Precise control of the innate immune response is required for resistance to microbial infections and maintenance of normal tissue homeostasis. Because this response involves coordinate regulation of h

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Gene expression in HeLa cells expressing GFP-IRF3 (non-targeting control and clonal knockouts of DDX58, MAVS, ATP13A1, CAPN15, TADA2B, MED16, and MED24) following Sendai virus (SeV) infection or hpRNA transfection. Gene expression in HeLa cells expressing GFP-IRF3 (non-targeting control and clonal knockouts of DDX58, MAVS, ATP13A1, CAPN15, TADA2B, MED16, and MED24) following Sendai virus (SeV) infection or hpRNA transfection

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CRISPR基因功能筛选

IRF3 translocates from the cytoplasm to the nucleus upon recognition of a cytoplasmic RNA stimulus by RIG-I or MDA5. Using an optical pooled CRISPR knockout screen in HeLa-Cas9 cells, we identified AT

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Genomic Redistribution of GR Monomers and Dimers Mediates the Transcriptional Response to Exogenous Glucocorticoid In Vivo.

激素受体转录组

巨噬细胞炎症

Expression profiles of GRdim mutant macrophages (mouse, bone-marrow derived) treated with LPS for 6 hrs or with LPS (6hrs) + Dex (O/N 1uM). Identification of GR-regulated genes in response to LPS. 3 G

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Structure of apo-SPO1 Tad2

蛋白质结构解析

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Structure of apo-SPO1 Tad2 Descriptor: Gp34.65 Authors: Xiao, Y, Feng, Y. Deposit date: 2023-09-25 Release date: 2024-09-25 Last modified: 2024-12-04 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Single ph

Protein Data Bank Japan2024-12-04 更新50

GEF-H1-IRF5 mediated gene expression changes in BMDM by MDP recognition. GEF-H1-IRF5 mediated gene expression changes in BMDM by MDP recognition

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防御基因表达

The transcription factor IRF5 is essential for immune defense against pathogens. Here, the authors show that the microtubule-associated factor GEF-H1 plays a critical role in host defense against List

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Genome-wide effect of ZBP1-mediated inflammatory response to LPS

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