Effect of EGFR activation on mouse chondrocytes
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资源简介：
We examined the change of chondrocyte transcriptome after EGFR activation by TGF-α and inhibition by gefitinib. Data analysis showed that EGFR activation down-regulates cartilage ECM biosynthesis and promotes ECM degradation. Gefitinib can reverse the effects of EGFR on chondrocytes. Cells: P2 mouse epiphyseal chondrocytes; Groups: Control (PBS), TGF-α (10 ng/ml, 48 h), TGF-α + Gefitinib (10 μM, 48 h)
创建时间：
2019-04-24
