Epigenetic and metabolic reprogramming by HDAC inhibition targets NRF2-active tumors [CUT&Tag]
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE220832
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资源简介：
To investigate the NRF2-specific cytotoxic effects of HDAC inhibition, we assessed genomic distribution of histone acetylation modifications and readers in the context of control and NRF2-overexpressing mouse LUAD cells upon HDAC inhibition. CUT&Tag of H3K27ac, H4ac (H4K5ac, H4K8ac, H4K12ac, H4K16ac) and BRD4 in KP1 EV and NRF2 cells treated with DMSO or Romidepsin.
创建时间：
2024-02-15
