Crystal structures of JAK1 and JAK2 inhibitor complexes

Crystal structures of JAK1 and JAK2 inhibitor complexes Descriptor: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase Authors: Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E. Deposit date: 2008-10-20 Release date: 2009-02-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. J.Mol.Biol., 387, 2009