Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos through inhibition of apoptosis. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA393309
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We generated hESCs with inducible expression of anti-apoptotic gene BCL2 and BCL2L1, and found that the BCL2- and BCL2L1-overexpression could inhibit apoptosis of hESCs without affecting their pluripotent state. Overall design: mRNA profiles of human embryonic stem cells with inducible expression of anti-apoptotic gene BCL2 and BCL2L1 were generated by RNA sequencing using Illumina HiSeq 4000
创建时间:
2017-07-06



